Endocrine Abstracts

Introduction: Metabolically associated fatty liver disease (MAFLD), prevalent in the Western world and a leading cause of liver transplantation among U.S. women, ranges from intra-hepatocyte lipid accumulation to cirrhosis. Fibrosis severity is crucial for prognosis, correlating with risks of advanced cirrhosis, portal hypertension, and hepatocellular carcinoma. 5-10% weight loss is associated with improvement of liver steatosis, but achieving >10% weight loss is usually n...